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Interesting article in the economist:
http://www.economist.com/node/18864354
“HELL is a city much like London,†opined Percy Bysshe Shelley in 1819. Modern academics agree. Last year Dutch researchers showed that city dwellers have a 21% higher risk of developing anxiety disorders than do their calmer rural countrymen, and a 39% higher risk of developing mood disorders. But exactly how the inner workings of the urban and rural minds cause this difference has remained obscureâ€â€until now.
Related article on NPR:
http://www.npr.org/templates/story/story.php?storyId=137345709
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